The methanolic extracts of stem and flower from cuscuta reflexa Roxb were investigated for antimicrobial and anthelmintic activity. The antibacterial activity was carried out against five pathogenic organism viz. Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi and Shigella sps, using methanolic extracts of stem and flower of C. reflexa. The zone of inhibition was determined against the bacteria at the concentration of 5, 10, 15 and 20% and among the bacteria tested Escherichia coli, was showed more resistant for the extracts used. Further, the anthelmintic activity of stem and flower extracts at 5 different concentrations (i.e., 2% to 10%) was performed on Indian earthworm Pheretima posthuma and albendazole used as standard reference. The results of the anthelmintic activity revealed that, all the test groups of the study exhibited reduction in time duration for the time of paralysis and death in both stem and flower extracts. Among them, stem extract was proved to be more potent than the flower extract. The phytochemical screening of the extracts revealed the presence of secondary metabolites like steroids, alkaloids, flavonoids, glycosides, phenols and tannins etc.
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